|
Sensitivities and specificities of WB rapid and panLF rapid tests evaluated at five institutions. |
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| WB rapid |
panLF rapid |
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|
|
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| Wb |
Bm/Bt |
*Other infec-tions |
Nor-mals |
Sens & Spec |
Wb |
Bm/Bt |
*Other infections |
Normals |
Sens & Spec |
|
|
|
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| UI |
43 (43) |
- |
0 (13) |
- |
100% sens 100% spec |
24 (24) |
35 (38) |
- |
- |
Overall sens: 95% Wb: 100% sens Bm: 92% sens |
| UM |
30 (30) |
- |
0 (58) |
0 (10) |
100% sens 100% spec |
30 (30) |
29 (29) |
0 (60) |
0 (10) |
100% sens (Bm & Wb) 100% spec |
| AMU |
102 (104) |
- |
- |
0 (48) |
98% sens 100% spec |
99 (104) |
- |
- |
0 (48) |
95% sens (Wb) 100% spec |
| USM |
47 (50) |
- |
1 (65) |
0 (50) |
94% sens 99% spec |
47 (50) |
109 (111) |
1 (65) |
0 (50) |
Overall sens: 97% Wb: 94% sens Bm: 98% sens 99% spec |
| ILS |
17 (18) |
- |
- |
- |
94% sens |
17 (18) |
- |
- |
- |
94% sens (Wb) |
|
Note: Numbers indicate number of samples that were positive, and numbers in parenthesis were the number of samples tested. UI : University of Indonesia, Indonesia UM : University of Malaya, Malaysia AMU : Aichii Medical University, Japan USM : Universiti Sains Malaysia, Malaysia ILS : Institute of Life Sciences, India sens : sensitivity; spec : specificity Wb: Wuchereria bancrofti ; Bm: Brugia malayi ; Bt: Brugia timori Filarial samples tested in Indonesia, Malaysia and India came from mf+ individuals; while those tested in Japan also came from individuals who are mf-, CFA+ (>512 units). *Other infections: ascariasis, trichuriasis, hookworm, strongyloidiasis, toxocariasis, toxoplasmosis, typhoid, cysticercosis, schistosomiasis, malaria, dengue, amoebiasis WB rapid: sensitivity : 97.6% (239/245); specificity : 99.6% (243/244) panLF rapid: overall sensitivity : 96.5% (390/404); sensitivity for Wb detection: 96.0% (217/226); sensitivity for Bm/Bt detection: 97.2% (173/178); specificity: 99.6% (232/233) | ||||||||||
Noordin et al. Filaria Journal 2007 6:9 doi:10.1186/1475-2883-6-9 |
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