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A convenient synthesis of γ-functionalized cyclopentenones

Nour Lahmar1, Taïcir Ben Ayed1, Moncef Bellassoued2 and Hassen Amri1

1Laboratoire de Chimie Organique & Organométallique, Faculté des Sciences, Campus Universitaire 2092-Tunis, Tunisie

2Laboratoire de Synthèse Organométallique, 5 mail Gay-Lussac, Neuville sur Oise, 95031 Cergy-Pontoise Cedex, France

Beilstein Journal of Organic Chemistry 2005, 1:11doi:10.1186/1860-5397-1-11

Published: 7 October 2005

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Abstract

The synthesis of γ-functionalized cyclopentenones was carried out in a few steps, starting firstly with the preparation of nitroketonic intermediates 2, which were readily transformed into 1,4-diketones using the Nef conversion. The intramolecular cyclization of the γ-diketones 3 in a basic medium, led to the functionalized cyclopentenones 4.

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