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Reactions of glycidyl derivatives with ambident nucleophiles; part 2: amino acid derivatives

Gerald Dyker1, Andreas Thöne1 and Gerald Henkel2

1Dept. of Chemistry & Biochemistry, Ruhr-University Bochum, Universitätsstrasse 150, D-44780 Bochum, Germany

2Dept. of Chemistry, Paderborn University, 33098 Paderborn, Germany

Beilstein Journal of Organic Chemistry 2007, 3:28doi:10.1186/1860-5397-3-28

Published: 27 September 2007

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Abstract

A three-step procedure for the synthesis of multifunctionalized heterocycles from a pyroglutamic acid derivative, glycidyl components and anilines by nucleophilic substitution and cobalt catalysis is presented.

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