 Full Research PaperUnexpected degradation of the bisphosphonate P-C-P bridge under mild conditionsPetri A Turhanen and Jouko J Vepsäläinen University of Kuopio, Department of Biosciences, Laboratory of Chemistry, PO Box 1627, FIN-70211, Kuopio, Finland Beilstein Journal of Organic Chemistry 2008,
4:7doi:10.1186/1860-5397-4-7
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21 January 2008 |
< previousabstractnext > Abstract
Unexpected degradation of the P-C-P bridge from novel bisphosphonate derivative 1a and known etidronate trimethyl ester (1b) has been observed under mild reaction conditions. A proposed reaction mechanism for the unexpected degradation of 1a and 1b is also reported.  < previousabstractnext > | 
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